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Knee Stem Cells in Patients with Heart Disease and Hypertension

Knee Stem Cells in Patients with Heart Disease and Hypertension

Knee Stem Cells in Patients with Heart Disease and Hypertension

Hypertension and coronary artery disease often are seen together. As our understanding of underlying causes of hypertension and coronary artery disease increase, key associated factors are integral to stem cell treatment.

Inflammation is a common denominator in joint arthritis, hypertension and coronary artery disease. Inflammation has been associated with obesity and the rise of inflammatory markers common in many diseases including diabetes and heart disease.

These inflammatory markers are also involved in Rheumatoid arthritis and degenerative osteoarthritis. Inflammation causes changes in blood vessels leading to plaque formation and atherosclerosis. This leads to less flexibility of blood vessels and high blood pressure ensues. These changes also lead to narrowing of the blood vessels to the heart resulting in coronary artery disease (CAD).

Stem cells may function in multiple ways, including regulating the inflammatory process. Studies are underway to use stem cells to treat heart attacks. However, this is after the fact. Prevention is still the obvious answer. Diet and obesity can all contribute to the progression of inflammation in blood vessels. These factors are important treatment as well as preventative measures.

Stem cells placed into patients who are obese or suffer from multiple systemic inflammatory disease processes, are always thrust into a harsher inflammatory environment than stem cells placed in your healthy patients.

This does not mean it is hopeless. In fact this is exactly why a highly skilled Regenerative Medicine physician is needed to deal with more complicated patients.

Treating knees with stem cells should not be a one size fits all patients practice.

Many factors control the fate and success of stem cells placed into a knee joint.

A key factor is the knowledge and experience of the physician treating your knee.

Dr. Dennis Lox is an expert in Sports and Regenerative Medicine. Dr. Lox understands the complexity of different patients and the need for individualized care. This approach ensures the best possible outcome.

Dr. Lox lectures on the National and International level on various Stem Cell related issues.

Avascular Necrosis (AVN) may occur from a variety of sources. Trauma is the leading cause of avascular necrosis (AVN). Spontaneous or insidious onset AVN is another common factor.

When more than one joint is diagnosed as having spontaneous avascular necrosis, an exhaustive search for other potential causes should be undertaken. Some patients may be a candidate for Stem Cell Therapy of more than one joint. If a proper evaluation suggests they may be a good candidate for several joint stem cell treatments, a proper understanding of whether the AVN is truly insidious or not is important.

Excessive corticosteroids (cortisone)
Excessive alcohol
Radiation therapy
Rheumatoid Arthritis
Gaucher’s disease
Caisson’s disease (decompression sickness)
Sickle cell disease

Spontaneous Avascular Necrosis

This term should be used when no other risk factor is present that may readily explain the condition. A times, remote corticosteroids during childhood for asthma, may be forgotten if the history is not very carefully structured.

Multiple trauma induced AVN, may also be diagnosed much later.

The effects of chemotherapy and radiation therapy may have many side effects as well, often confusing early diagnosis. With many possible risk associated factors, Spontaneous AVN should be used hesitantly in AVN occurring in multiple sites without exhausting other potential causes.

Treatment of AVN with Stem Cell Therapy

The treatment of avascular necrosis with Stem Cell Therapy should be with a Regenerative Medicine physician who has experience treating AVN. The complexities of treating AVN, as well as the issues of patient specific goals, needs, or sports participation is highly important for the patient, and in arriving at a treatment plan.