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Knee Stem Cells for Arthritis, Osteoarthritis, Meniscus Tears, Rheumatoid Arthritis, Knee Bursitis and Knee Surgery Alternative
Los Angeles Metro Area Call (310) 975-7033

Dennis M. Lox, M.D. Knee Stem Cell Treatments have been seen Across The Nation.

Dennis M. Lox M.D. Knee Stem Cell Treatments have been seen Across The Nation.

Since 1990, Dennis M. Lox, M.D. has been helping patients increase their quality of life by reducing their pain.  He emphasizes non-surgical treatments and appropriate use of medications, if needed. Dennis M Lox M.D. is an expert in Knee Stem Cell Injections for those who seek an alternative to the unnecessary complex knee surgery of that in the past by providing Knee Stem Cell Treatment. Dennis M. Lox, M.D. has privately owned Medical Centers that do not partake in the fast chain franchise that other Stem Cell Centers are stuck doing, thus he is able provide a more personalized treatment for your particular injury.

Dennis M. Lox M.D. centers have a professional, caring environment for patients looking for comfort in their time of need and provids follow-ups on your wellbeing to enhance your recovery.


Each week, Dennis M. Lox M.D. receives inquiries from around the world regarding stem cell therapy.
Each week, Dennis M. Lox M.D. receives inquiries from around the world regarding stem cell therapy.

Call (310) 975-7033 for a Knee Stem Cell Consultation


Knee Stem Cells for Arthritis and Joint Injuries


This is an interesting point. First, what is our definition of arthritis?

Second, what affect do stem cells exert upon the arthritic knee joint?

The most typical reference to arthritis is for osteoarthritis. Osteoarthritis is typically associated with wear and tear, yet it is much more complex. Rheumatoid arthritis is much less common than osteoarthritis, and is an autoimmune disorder.

Stem cells may exert several roles in the repair of knee osteoarthritis. Stem cells may act as anti-inflammatory mediators, and stem cells may form new cartilage or bone cells, by differentiation.


A working definition of knee osteoarthritis is the degeneration of the knee joint. The knee is composed of cartilage and bone. When the cartilage wears sufficiently, the underlying bone degrades, and the joint is compromised. The spectrum of knee joint osteoarthritis is from the beginning to the end stage. The onset of knee arthritis may occur from trauma. This imparts a set ground zero for the development of knee osteoarthritis. This trauma may resolve without knee continued knee pain, however the destructive process has occurred. The normal knee is in a state of balance between knee cartilage breakdown and repair. When breakdown exceeds repair, degeneration occurs. Over time the spectrum of osteoarthritis is magnified and at this point x-ray or MRI changes may be seen. Initial subclinical knee osteoarthritis is not visualized on imaging such as x-Rays. It may be thought of as a chemical imbalance of the knee joint.

Inflammatory chemicals or mediators breakdown the knee, while anti-inflammatory mediators repair the knee joint. Simply stated knee arthritis is there before you you really know it.

That is the bad news. This imparts a meeting of Preventative and Regenerative Medicine. An ounce of prevention is worth a pound of cure. That could be extrapolated many ways in stem cell medicine.


Regenerative Medicine is the emerging field of study in which science and medicine merge to use repair and regenerative strategies to aid the body to heal itself.

Stem cells are a part of Regenerative Medicine. The body may utilize many methods to heal, yet in degenerative arthritis, the body is incapable of healing itself. Stem cells are not found in knee osteoarthritic joints, or are of insufficient quantities to mount a healing response in the presence of joint degenerative mediators. This is why knee osteoarthritis occurs. The body simply cannot heal itself.

Listen to 620 WDAE Radio, Ian Beckles, Ron Diaz and Dennis M. Lox M.D. talk about Ian Beckles Stem Cells Procedure and how well they performed for him.


To overcome the body’s own limitations to heal itself, stem cells may be directly injected into the knee joint. This may alter the degenerative cascade and favor an environment of repair, rather than knee cartilage breakdown.

Knee stem cell injections may be preformed by an experienced specialist. There are many factors involved in the successful treatment of knee osteoarthritis. Simplistic cookie cutter templates or franchise approaches to knee pain is fraught with dilemmas.

Each individual has unique characteristics that will impart decision making in the treatment approach and success rate. Caution should be exercised when evaluating stated claims of success rates. A unique individual is not a grape on a vine. The individual is an apple amongst an array of oranges, peaches, mangos, and grapefruits. Individual are highly different. A 20 year old knee is not the same as an 80 year old knee. A professional athletes knee may be more advanced than their stated age, despite their gifted genetics.

A clinical study of stem cells injected into the knees of patients one week after surgery, failed to recognize this. Patients were between the ages of 18-65. Each patient had at least 50% of their knee meniscus removed 1 week prior to the stem cell injections. There were multiple different surgeons at multiple hospitals across the United States. There were some successes of knee regeneration, among the majority of no regeneration of the knees. Any regeneration is not possible with surgery alone. This illustrates the complexities of patients as individuals. Lumping patients into categories of results based on such different factors is inherently destined to failure.


Having been introduced to the concepts outlined in paragraph one, we may now attempt an answer…..Maybe sometimes.

If knee arthritis is a spectrum over time, how many patients will present at ground zero or close to a model which may be completely repaired?

Few. This is because as we age, each day we are a little bit older, including our joints. There is no fountain of youth as of yet. Therefore the best we can achieve is the optimal response for the period of time “we elect” to have stem cells. We know x-Rays may significantly change over a 3-5 year period. The most optimal time to have stem cells may have already passed before the patient considers to have stem cells. THIS DOES NOT MEAN IT IS TOO LATE TO TREAT.

This must be reiterated, perfect timing in anything is rarely achieved. We must remember the crossroads of Preventative Medicine and Regenerative Medicine. If we have not prevented, we are always somewhere in between prevention and regeneration. This is advanced reading material. When this is understood, concepts like success rates from a variable medical practice that does cosmetic procedures and part time knees are better understood.


Discuss your case with an experienced specialist. Use caution when evaluating claims.
Become knowledgeable to be part of your medical decision making process.
An informed patient can make informed decisions.